Table. 5.

Table. 5.

Iron preparations for intravenous use

Formulation Brand name Dosage form Usage and dose
Ferric hydroxide sucrose complex Venostin inj. 2,700 mg/5 mL Intravenous infusion
Venoferrum inj. (Fe3+ 20 mg/mL) -Dilution: mix 5 mL+100 mL NS
Anerrum inj. -Maximum dose: 7 mg/kg (Max Fe3+ 500 mg), child 3 mg/kg
Ferrovin inj. -Infusion rate: 100 mg for 15 min or more, if maximum dose, over than 3 h 30 mins
Ferrowell inj. Intravenous direct injection
Femorrum inj. -Maximum dose: 10 mL (Fe3+ 200 mg)
Ferex inj. -Injection rate: slow than 1 mL/min
Iron isomaltoside Monofer inj. 417 mg/mL Intravenous infusion
(Fe3+ 100 mg/mL), -Dilution: mix 2 mL+500 mL NS
-Maximum dose: 20 mg/kg (Max Fe3+ 500 mg)
-Infusion rate: ≤1,000 mg, for 30 mins, >1,000 mg, for 60 mins
Intravenous direct injection
-Maximum dose: Fe3+ 500 mg
-Injection rate: 50 mg/min
-Do not mix or 20 mL NS mix
Ferric hydroxide carboxymaltose complex Ferinject inj. 180 mg/mL Intravenous infusion
(Fe3+ 50 mg/mL) -Maximum dose: Fe3+ 1,000 mg
-Dilution and infusion rate
2-4 mL+50 mL NS, No prescribed infusion rate
4-10 mL+100 mL NS, over 6 mins
10-20 mL+250 mL NS, over 15 mins
(Do not mix under Fe 2 mg/mL dilution)
Intravenous direct injection
-Maximum dose: Fe3+ 1,000 mg
-Injection rate: Same as Intravenous infusion rate

NS, normal saline

Clin Pediatr Hematol Oncol 2020;27:101-12
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