Table. 6.

Table. 6.

Indication and contraindication for parenteral iron therapy [3,31,33]

Indication
Chronic inflammatory bowel disease (active disease or hemoglobin <10 g/dL) or situations with proven malabsorption
Chronic kidney disease on hemodialysis or with ESA treatment
Iron-refractory iron deficiency anemia
Chronic heart disease (systolic, NYHA class II-IV)
Chronic bleeding with a uncorrectable etiology, where oral therapy is insufficiently effective or contraindicated
Failure to achieve correction of IDA after well-conducted oral iron substitution, in the setting of good adherence
Pregnancy (thirdtrimester and second trimester if hemoglobin <10.5 g/dL)
Contraindication
Presence of an active/acute infection
Personal history of drug anaphylaxis/allergy
Tractable comorbidity explaining the signs and symptoms
A desire to increase school/academic or sports performance in the absence of laboratory tests confirming IDA

NYHA, New York Heart Association; IDA, iron deficiency anemia

Clin Pediatr Hematol Oncol 2020;27:101-12
© 2020 Clin Pediatr Hematol Oncol