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Case Report
Two Pediatric Cases of Spontaneous Ruptured Solid Tumors Successfully Treated with Transcutaneous Arterial Embolization
Clin Pediatr Hematol Oncol 2018;25:197-201.
Published online October 31, 2018
© 2018 Korean Society of Pediatric Hematology-Oncology and Korean Society for Pediatric Neuro-Oncology

Kyo Jin Jo, M.D.1, Eu Jeen Yang, M.D.1, Kyung Mi Park, M.D.1, Jin Heyok Kim, M.D.2, Ung Bae Jeon, M.D.2, Joo Yeon Jang, M.D.2 and Young Tak Lim, M.D.1

1Department of Pediatrics, Pusan National University Children’s Hospital, 2Department of Radiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea
Correspondence to: Young Tak Lim
Department of Pediatrics, Pusan National University Children’s Hospital, 20 Geumo-ro, Meulgeum-eup, Yangsan 50612, Korea
Tel: +82-55-360-2180
Fax: +82-55-360-2181
Received September 12, 2018; Revised September 28, 2018; Accepted October 5, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Spontaneous rupture with internal bleeding of solid tumors has rarely been described at the time of diagnosis or during chemotherapy. This rare event must be regarded as a life threatening condition. In these emergency situations, control of hemorrhage, which is life-saving, can be achieved by transcatheter arterial embolization (TAE) and/or surgical resection. This report describes two infants presenting with acute hemorrhagic shock due to spontaneous tumor rupture of hepatoblastoma and neuroblastoma during chemotherapy. TAE successfully arrested the tumor bleeding and a visibly reduced the tumor size in both children. Spontaneous rupture of solid tumors occur infrequently in children, but is a life threatening situation. Careful monitoring for the occurrence of this rare event especially in very young children presenting with a large tumor mass.
Keywords: Ruptured solid tumor, Transcatheter arterial embolization, Children
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October 2018, 25 (2)
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Author ORCID Information
  • Young Tak Lim 

Funding Information
  • Pusan National University Yangsan Hospital