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Case Report
A Case of Pediatric Acute Lymphoblastic Leukemia with Trisomy 5 as a Sole Chromosomal Anomaly: A Prognostic Significance
Clin Pediatr Hematol Oncol 2019;26:91-4.
Published online October 31, 2019
© 2019 Korean Society of Pediatric Hematology-Oncology and Korean Society for Pediatric Neuro-Oncology

Young Hwan Cho and In-sang Jeon

Department of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea
Correspondence to: In-sang Jeon
Department of Pediatrics, Gachon University Gil Medical Center, 14 Namdongdaero 774 beongil, Namdong-gu, Incheon 21565, Korea
Tel: +82-32-460-8382
Fax: +82-32-460-3224
E-mail: isjeon@gilhospital.com
ORCID ID: orcid.org/0000-0001-8714-9403
Received July 31, 2019; Revised August 26, 2019; Accepted September 24, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
We present a case of Korean pediatric patient with pre-B cell type acute lymphoblastic leukemia (ALL) with trisomy 5 as a sole cytogenetic anomaly. Here, we compare and describe the present case with previous pediatric case reports and provide a review of the literature. This case report may help elucidate the poor prognostic impact of trisomy 5 as a sole cytogenetic anomaly in pediatric patients with ALL. Additional studies are needed to confirm this hypothesis.
Keywords: Trisomy 5, Acute lymphoblastic leukemia, Prognosis, Pediatrics
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October 2019, 26 (2)
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  • In-sang Jeon