Table. 1.

Table. 1.

The change of immunoglobulin levels and real time PCR results of Epstein-Barr virus (EBV) and cytomegalovirus (CMV) according to clinical course including chemotherapy with rituximab, recurrent infections, and low dose prednisolone with regular intravenous immunoglobulin

Care for patient Chemotherapy with rituximab Post chemotherapy ↓ (IVIG) ↓ (IVIG) ↓ (IVIG)
1st cycle 3rd cycle
Age (years old) 1.6 1.9 4.2 8.3 8.5 9.5
EBV (copies/mL) 176,772 5,589 N/E Not detected Not detected
CMV (copies/mL) 215,153 3,444 N/E Not detected Not detected
IgG (mg/dL) 889 575 135 30 300 474
IgM (mg/dL) 54 20 N/E 36 18 33
IgA (mg/dL) 45 33 N/E <1.0 <1.0 <1.0
Patient status EBV associated lymphoma Recurrent Infections Low dose prednisolone with IVIG infusion according to IgG level

EBV, Epstein-Barr virus; CMV, cytomegalovirus; Ig, immunoglobulin; IVIG, intravenous immunoglobulin; N/E, not evaluated.

Clin Pediatr Hematol Oncol 2021;28:84-8
© 2021 Clin Pediatr Hematol Oncol