Fig. 1. (A) The computed tomo-graphy of the patient’s brain at admission shows a 6.5 cm acute intracranial hemorrhage in the left frontal lobe with perilesional edema and midline shifting to the right. (B) An initial peripheral blood smear reveals left-shifted myeloid hyper-plasia with dysplasia (myeloblasts 2%, myelocytes 20% and metamy-elocytes 3% of the leukocytes) (Weight-Giemsa stain, ×400). (C) A bone marrow smear reveals in-creased granulocytic series with 8.7% myeloblasts and dysgranulo-poiesis (Weight-Giemsa stain, ×400). (D) A follow-up bone marrow smear of the patient 3 months after the initial evaluation shows increased myeloblasts of 14% (Weight-Giemsa stain, ×400). (E) Magnetic reson-ance imaging of brain 11 months later shows en-cephalomalacic change with hemo-siderin deposit in left frontal lobe and corpus callosum, sequelae of previous intracranial hemorrhage.
Clin Pediatr Hematol Oncol 2021;28:93-7
© 2021 Clin Pediatr Hematol Oncol