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Case Report
Two Pediatric Cases of Spontaneous Ruptured Solid Tumors Successfully Treated with Transcutaneous Arterial Embolization
Clin Pediatr Hematol Oncol 2018;25:197-201.
Published online October 31, 2018
© 2018 Korean Society of Pediatric Hematology-Oncology

Kyo Jin Jo, M.D.1, Eu Jeen Yang, M.D.1, Kyung Mi Park, M.D.1, Jin Heyok Kim, M.D.2, Ung Bae Jeon, M.D.2, Joo Yeon Jang, M.D.2 and Young Tak Lim, M.D.1

1Department of Pediatrics, Pusan National University Children’s Hospital, 2Department of Radiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea
Correspondence to: Young Tak Lim
Department of Pediatrics, Pusan National University Children’s Hospital, 20 Geumo-ro, Meulgeum-eup, Yangsan 50612, Korea
Tel: +82-55-360-2180
Fax: +82-55-360-2181
E-mail: limyt@pusan.ac.kr
ORCID ID: orcid.org/0000-0002-3300-7239
Received September 12, 2018; Revised September 28, 2018; Accepted October 5, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Spontaneous rupture with internal bleeding of solid tumors has rarely been described at the time of diagnosis or during chemotherapy. This rare event must be regarded as a life threatening condition. In these emergency situations, control of hemorrhage, which is life-saving, can be achieved by transcatheter arterial embolization (TAE) and/or surgical resection. This report describes two infants presenting with acute hemorrhagic shock due to spontaneous tumor rupture of hepatoblastoma and neuroblastoma during chemotherapy. TAE successfully arrested the tumor bleeding and a visibly reduced the tumor size in both children. Spontaneous rupture of solid tumors occur infrequently in children, but is a life threatening situation. Careful monitoring for the occurrence of this rare event especially in very young children presenting with a large tumor mass.
Keywords: Ruptured solid tumor, Transcatheter arterial embolization, Children
References
  1. Kitahara S, Makuuchi M, Ishizone S, et al. Successful left trisegmentectomy for ruptured hepatoblastoma using intraoperative transarterial embolization. J Pediatr Surg 1995;30:1709-12.
    CrossRef
  2. Honda S, Miyagi H, Minato M, Kubota KC, Okada T. Hemorrhagic shock due to spontaneous rupture of adrenal neuroblastoma in an infant: a rare case and review of the literature. J Pediatr Hematol Oncol 2012;34:635-7.
    Pubmed CrossRef
  3. Chan KL, Fan ST, Tam PK, Chiang AK, Chan GC, Ha SY. Management of spontaneously ruptured hepatoblastoma in infancy. Med Pediatr Oncol 2002;38:137-8.
    Pubmed CrossRef
  4. Krauel L, Albert A, Mora J, et al. Use of angioembolization as an effective technique for the management of pediatric solid tumors. J Pediatr Surg 2009;44:1848-55.
    Pubmed CrossRef
  5. Hansen ME, Kadir S. Elective and emergency embolotherapy in children and adolescents. Efficacy and safety. Radiologe 1990;30:331-6.
    Pubmed
  6. Meersman A, Wojciechowski M, Vaneerdeweg W, Jorens P, Michiels E, Ramet J. Acute retroperitoneal hemorrhage and shock as presenting signs of neuroblastoma in an infant. Pediatr Emerg Care 2008;24:37-8.
    Pubmed CrossRef
  7. Normand C, Leblond P, Mazingue F, Nelken B, Defachelles AS, Bonnevalle M. A case of adrenal haemorrhage after minor trauma in a young child: think of neuroblastoma. Eur J Pediatr Surg 2006;16:365-8.
    Pubmed CrossRef
  8. Yoshiya S, Iwaki K, Sakai A, et al. Laparoscopic left hepatectomy for ruptured hepatocellular carcinoma controlled after transcatheter arterial embolization: case report and review of the literature. In Vivo 2018;32:659-62.
    Pubmed KoreaMed
  9. Madanur MA, Battula N, Davenport M, Dhawan A, Rela M. Staged resection for a ruptured hepatoblastoma: a 6-year followup. Pediatr Surg Int 2007;23:609-11.
    Pubmed CrossRef
  10. Saettini F, Conter V, Da Dalt L, et al. Ruptured hepatoblastoma:A case report and literature review. J Solid Tumors 2013;3:46-50.
    CrossRef
  11. Chan KL, Tam PK. Successful right trisegmentectomy for ruptured hepatoblastoma with preoperative transcatheter arterial embolization. J Pediatr Surg 1998;33:783-6.
    CrossRef
  12. Iida T, Suenaga M, Takeuchi Y, et al. Successful resection of a ruptured hepatoblastoma prior to chemotherapy: report of a case. Surg Today 2004;34:710-4.
    Pubmed CrossRef
  13. Rilling WS, Chen GW. Preoperative embolization. Semin Intervent Radiol 2004;21:3-9.
    Pubmed KoreaMed CrossRef
  14. Kickuth R, Waldherr C, Hoppe H, et al. Interventional management of hypervascular osseous metastasis: role of embolotherapy before orthopedic tumor resection and bone stabilization. AJR Am J Roentgenol 2008;191:240-7.
    Pubmed CrossRef
  15. Yoshida H, Mamada Y, Taniai N, Uchida E. Spontaneous ruptured hepatocellular carcinoma. Hepatol Res 2016;46:13-21.
    Pubmed CrossRef


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  • Young Tak Lim 

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  • Pusan National University Yangsan Hospital