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  • How I Treat Primary Immune Deficiencies with Hematopoietic Stem Cell Transplantation

    Conditioning regimens for PID recommended by EBMT/ESID inborn errors working party [14]. Protocol A and B: These are recommended for patients without severe preexisting organ damage and non-SCID diseases where a complete donor chimerism is desired for optimal disease correction. Protocols C and D: These are recommended for patients with preexisting organ damage and/or diseases where engraftment has been shown to reliably occur with reduced intensity conditioning. Mixed donor chimerism is more likely to occur compared to protocols A and B. Protocol E: This may be best suited for patients with preexisting organ damage and/or diseases where full myeloid engraftment is not absolutely required. Higher degrees of chimerism can be achieved when using PBSC. DLI may be required in case of mixed chimerism. Protocol F: To avoid organ toxicity this regimen is only recommended for patients with DNA repair/radio-sensitivity disorders (except Artemis deficiency) in which alkylating agents are used in low dose. PID, primary immune deficiencies; EBMT, European Society for Blood and Marrow Transplantation; ESID, European Society for Immune Deficiencies; SCID, severe combined immunodeficiency; PBSC, peripheral blood stem cell; DLI, donor lymphocyte infusion.

  • IVIG Treatment Response and Age are Important for the Prognosis of Pediatric Immune Thrombocytopenia

    Relationship between age and disease phase. (A) Number of patients by disease phase. (B) Number of patients with disease phase by age group.

Clin Pediatr Hematol Oncol 2023;30:53-104
Review Article
Childhood Neuroendocrine Tumors of Appendix: Suggested Approach and Management
Muhammad Matloob Alam, Abdulrhman Alathaibi, Mohamed Magdi Refai, Abdulaziz Alsaedi and Muhammad Usman Tariq
Clin Pediatr Hematol Oncol 2023;30:53-9.
Original Article
Status and Needs for the Return to School of Childhood and Adolescent Cancer Survivors
Eun Sil Park, Eun Young Ju, Jae Young Lim, Hyun Sik Kang, Jin Kyung Suh, Meerim Park, Jun Ah Lee, Bo-Yoon Jeong, Young Ae Kim and Hyeon Jin Park
Clin Pediatr Hematol Oncol 2023;30:60-9.
Case Reports
Lineage Switch Subsequently Developed after Isolated Extramedullary Relapse in Children with Acute Myeloid Leukemia
Yee Rae Park, Eu Jeen Yang, Ju Kyung Hyun, Ina Jeong, In-Sook Kim and Young Tak Lim
Clin Pediatr Hematol Oncol 2023;30:70-4.
Two Cases of Chronic Myeloid Leukemia in Lymphoid Blast Phase Presented as Philadelphia-Positive Acute Lymphoblastic Leukemia
Tae Hoon Lee, Hee Young Ju, Ji Won Lee, Ki Woong Sung and Keon Hee Yoo
Clin Pediatr Hematol Oncol 2023;30:75-9.
Case of Chronic Active Epstein-Barr Virus Infection Developed Hemophagocytic Lymphohistiocytosis after COVID-19 Infection
Sumin Jo, Hye Lim Jung, Sooyeon Lim, Eun Sil Kim, Aram Yang, Ji Hee Kwak, Deok Soo Kim, Jung Yeon Shim and Jae Won Shim
Clin Pediatr Hematol Oncol 2023;30:80-4.
Three Case Reports of Pediatric Collagenous Gastritis with Recurrent Iron Deficiency Anemia
Tae Hwan Kim, Sumin Yoo and In Hyuk Yoo
Clin Pediatr Hematol Oncol 2023;30:85-90.
Successful Treatment of Autoimmune Hemolytic Anemia with Sirolimus after Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report
Hyun Jin Park, Jung Yoon Choi, Kyung Taek Hong, Bo Kyung Kim and Hyoung Jin Kang
Clin Pediatr Hematol Oncol 2023;30:91-4.
A Case of Bernard-Soulier Syndrome Associated with 22q11.2 Deletion Syndrome
Oh Cheol Kwon, Su Hyun Yoon, Sung Han Kang, Hyery Kim, Kyung-Nam Koh and Ho Joon Im
Clin Pediatr Hematol Oncol 2023;30:95-8.
Loeys-Dietz Syndrome with Type 1 Diabetes Mellitus
Daro Jeong, Jung Hyun Lee and Seom Gim Kong
Clin Pediatr Hematol Oncol 2023;30:99-102.
Letter To The Editor
Radiotherapy for Childhood Cancer
Sung Eun Kim and Jeong Eun Lee
Clin Pediatr Hematol Oncol 2023;30:103-4.

October 2023, 30 (2) :53-104
Clin Pediatr Hematol Oncol


ISSN 2233-5250 (Print edition)
ISSN 2233-4580 (Online edition)
Phone: +82-2-516-6581
Fax: +82-2-516-6582
E-mail: journal@cpho.or.kr

  • Aims and Scope
Clinical Pediatric Hematology-Oncology (Clin Pediatr Hematol Oncol, CPHO) is a peer-reviewed open-access journal and the official journal of the Korean Society of Pediatric Hematology-Oncology (KSPHO). CPHO aims to deliver new and important scientific knowledge and information regarding clinical and biological aspects of the pediatric hematology and oncology to contribute to healthcare of children, adolescents and young adults. more
Basic Understanding of Iron Metabolism
Jin Kyung Suh, M.D., Ph.D., In-sang Jeon, M.D.
Received March 26, 2018; Accepted April 9, 2018.
Vascular Anomaly: An Updated Review
Meerim Park
Received March 24, 2019; Accepted April 6, 2019.
A Recent Update on Histiocytic Disorder in Children: Focus on Diagnosis and Treatment
Hoi Soo Yoon
Received April 6, 2020; Accepted April 21, 2020.
Hemophagocytic Lymphohistiocytosis
Sun Young Park, M.D. and Jae Min Lee, M.D.
Received March 26, 2017; Accepted April 21, 2017.